ARCHIVE SEARCH
      -OR-  
 
  NEWS CHANNELS
Fitness News
Asthma Allergy News
 > Diabetes News
Women's Health News
Men's Health News

  MY NEWS
Personal Archive
My Account

  ABOUT THIS NEWSFEED
About Us
Advertise With Us
Feed Your Site
Contact Us


Site Map
RSS News Feed 

  Website development & hosting
   by Cyber Software Solutions

 
Resveratrol Has No Effect in Healthy Obese Men, Study Finds
Data raise doubts about its use as a human nutritional supplement in metabolic disorder

MONDAY, April 8 (HealthDay News) -- Resveratrol appears not to have a metabolic effect in obese men, according to a study published in the April issue of Diabetes.

Noting that animal and in vitro studies have indicated that resveratrol has an effect on obesity, diabetes, hypertension, and hyperlipidemia, Morten M. Poulsen, M.D., from Aarhus University Hospital in Denmark, and colleagues examined the metabolic effects of high-dose resveratrol in 24 obese, but otherwise healthy, men. Participants were randomized to four weeks of resveratrol or placebo.

The researchers found that there was a non-significant decrease in insulin sensitivity in both groups. No change was noted in endogenous glucose production or in the turnover and oxidation rates of glucose. No impact was noted for resveratrol supplementation on blood pressure, resting energy expenditure, lipid oxidation rates, ectopic or visceral fat content, or inflammatory and metabolic biomarkers.

"The lack of effect disagrees with persuasive data obtained from rodent models and raises doubt about the justification of resveratrol as a human nutritional supplement in metabolic disorders," the authors write.

The study was partially funded by the Novo Nordisk Foundation.

Abstract
Full Text (subscription or payment may be required)
Editorial



Health News Copyright © 2013 HealthDay. All rights reserved.


Back to Top Stories
  GOOGLE ADS