ARCHIVE SEARCH
      -OR-  
 
  NEWS CHANNELS
Fitness News
Asthma Allergy News
 > Diabetes News
Women's Health News
Men's Health News

  MY NEWS
Personal Archive
My Account

  ABOUT THIS NEWSFEED
About Us
Advertise With Us
Feed Your Site
Contact Us


Site Map
RSS News Feed 

  Website development & hosting
   by Cyber Software Solutions

 
Cardiac Autonomic Dysfunction Is Linked to Arterial Stiffness
Association may boost risk for cardiovascular disease in those with type 1 diabetes

WEDNESDAY, April 3 (HealthDay News) -- Cardiac autonomic dysfunction as measured by lower heart rate variability (HRV) is associated with increases in both central and vascular vascular stiffness among youths with type 1 diabetes regardless of underlying cardiovascular disease (CVD) risk factors, according to research published online Feb. 22 in Diabetes Care.

Mamta Jaiswal, M.B.B.S, Ph.D., of the Colorado School of Public Health in Aurora, and colleagues conducted a sub-study to the SEARCH for Diabetes in Youth Study to explore the associations between reduced HRV and increased arterial stiffness (AS) in 344 youth with type 1 diabetes and 171 youth without.

According to the researchers, in youths with type 1 diabetes, lower HRV, as measured by SD of normal R-R interval (SDNN), was associated with lower brachial distensibility (BrachD), a marker of peripheral AS (P = 0.01), and higher pulse wave velocity in the carotid to femoral segment (PWV-trunk) (P = 0.0001), as well as a higher augmentation index adjusted for heart rate of 75 beats per min (AIx75), (P = 0.007), markers for central AS. Adjustment for CVD risk factors attenuated these associations, except for BrachD and PWV-trunk. Although a similar association was observed between HRV and BrachD in youth controls, lower HRV was not associated with higher PWV-trunk and AIx75.

"We found a strong association between cardiac autonomic dysfunction and both central and peripheral AS in youth with type 1 diabetes, independent of traditional CVD risk factors," the authors write. "While lower HRV was also associated with increased peripheral stiffness in non-diabetic control youth, the association with central stiffness may be unique to individuals with type 1 diabetes. This association may contribute to the increased and premature cardiovascular disease burden in people with type 1 diabetes."

Abstract
Full Text (subscription or payment may be required)



Health News Copyright © 2013 HealthDay. All rights reserved.


Back to Top Stories
  GOOGLE ADS